Lex Luthor, who is portrayed by Michael Rosenbaum, was a series regular on Smallville from the first season until the seventh.  Lex, of course, grows up to be Superman's infamous arch-nemesis.

Lex Luthor Quotes

Lex: Clark...do you believe a man can fly?
Clark: Sure. In a plane.
Lex: No, I'm not talking about that. I'm talking about soaring through the clouds, with nothing but air beneath you.
Clark: People can't fly, Lex.
Lex: I did. After the accident, when my heart stopped. It was the most exhilarating two minutes of my life. I flew over Smallville, and for the first time, I didn't see a dead end. I saw a new beginning. Thanks to you, I have a second chance. We have a future, Clark, and I don't want anything to stand in the way of our friendship.

Clark: Hey, this is a great place.
Lex: Yeah, if you're dead and in the market for something to haunt.
Clark: Well, I meant it's roomy.
Lex: It's the Luthor ancestral home, or so my father claims. He had it shipped over from Scotland stone by stone.
Clark: Yeah, I remember. The trucks rolled through town for weeks but no one ever moved in.
Lex: My father had no intention of living here. He's never even stepped through the front door.
Clark: Then why'd he ship it over?
Lex: Because he could.

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Smallville Quotes

I saw me, I mean, Clark Kent, disguised behind glasses and a bad haircut.

Clark

We'll have a better chance surviving your dad's desert than Zod's Thunderdome.

Oliver