James Wilson is the Head of the Department of Oncology at Princeton Plainsboro.

He serves as House's best friend and foil. The pair get along in a strange way, often relying on one another for both advice and insults.

Wilson seems to understand House in a way no one else can. He serves to enable, and to assist, his pal.

Dr. James Wilson Quotes

House: We are condemned to useless labor...
Dr. Wilson: Fourth circle of hell. Charting goes a lot faster when you eliminate all classic poetry.
House: Writing down what we already know to be read by nobody. Pretty sure Dante would agree that qualifies as useless.
Dr. Wilson: You're over two weeks behind in your charting...
(Dr. Cuddy approaches them, and House throws a piece of paper towards her)
House: Oops... I missed!

Dr. Cuddy: And is there a paternity bet on the father of the patient?
House: Doesn't sound like me.
Dr. Wilson: Well, it does, actually, but doesn't mean you're guilty.

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House Quotes

Our entire relationship is about you. My dying is about me!

Wilson

[To Foreman} That'd be redundant. I've got an angry black guy waiting for me to drop the soap right here.

House