As we discussed in our review of last night's episode, Grey's Anatomy delivered many dramatic developments on Thursday, casting relationships far and wide into doubt.

Below are some of the best quotes from the episode. Check out some of our favorite lines and follow the link for Grey's Anatomy quotes from every episode since 2005!

Mark: [to Lexie] I can't even look at you right now. | permalink

Owen: People do matter. I matter. We matter. | permalink

Alex: I want you to go and be happy and not come back. | permalink

Arizona: He makes scratching look sexy.
Lexie: He makes everything look sexy. | permalink

Miranda: The Chief is gone... he's been gone a long time. | permalink

Izzie: Surgery. It's the thing you come home from, not the thing you come home to. | permalink

Meredith: Izzie leaves and Mark gets a kid, and you two decide the best way to deal is to get drunk and mash your genitals together?
Alex: No freaking way you get to judge us or give relationship advice. Besides you were a total dirty mistress like two weeks ago.
Lexie: Are we calling me a dirty mistress?
Meredith: That was two years ago and his wife didn't have cancer!
Lexie: Because I've been with like six guys in my whole life. Alex and I, we've done it before. I was recycling, it was like good for the environment.
Alex: Izzie's gone. I was horny. She was there.
Lexie: Oh crap, I am a dirty mistress! | permalink

Meredith: (narrating) Number one rule of surgery is limit exposure. Keep your hands clean, your incisions small, and your wounds covered. Number two rule of surgery is when rule number one stops working, try something else. Because sometimes you can't limit exposure, sometimes the injury is so bad you have to cut, and cut big. | permalink

Steve Marsi is the Managing Editor of TV Fanatic. Follow him on Google+ or email him here.